Short answer: Willow sells compounded semaglutide for $299 a month all-in, and Hims sells FDA-approved GLP-1s from $298 a month all-in. For…
September 22, 2026
Success by Sesame Review 2026: Real Cost, Medications and Safety
FDA-approved GLP-1s: $99/month care plan ($59 annual) plus medication, e.g. Wegovy pill from $149. All-in from $248/month. Checked Sept 21, 2026.
Quick verdict
Independent review of
Sesame sesamecare.com
- Official prices checked September 21, 2026
- No affiliate relationship
- FDA-approved medications
7.1/10 our score
Official site ↗- Best for
- Costco members who want FDA-approved GLP-1s
- Starting price
- $248/mo
- Key feature
- Costco Pharmacy pricing plus included labs
Success by Sesame suits Costco members who want FDA-approved medication with a choice of provider and included labs. Without a Costco membership, or if you want home delivery, other programs are simpler.
Our rating
Pricing
Wegovy pill starter dose + care plan
$248/mo
- Medication $149 + care plan $99
- Annual care plan: $59/mo
Wegovy pill maintenance + care plan
$398/mo
- Medication $299 + care plan $99
- With annual care plan: $358/mo
Zepbound vials + care plan
$398/mo
- Medication from $299 (LillyDirect) + care plan $99
Wegovy or Ozempic injection at Costco + care plan
$448/mo
- Medication $349 at Costco Pharmacy + care plan $99
- New patients: $199 medication for the first two months
- Costco membership required
Prices can change. Check the provider’s site for current pricing. Last checked September 21, 2026.
Pros and cons
Pros
- Video visits and labs included in the care plan
- Low Costco Pharmacy cash price for Wegovy and Ozempic injections
- Annual plan lowers care cost to $59/month
- FDA-approved medications only
Cons
- Care plan and medication billed separately
- Costco pricing requires a Costco membership and in-store pickup
- No compounded options
Features
Video visitsIncluded in care plan
LabsIncluded in care plan
FDA-approved medicationBrand-name only
Insurance helpPrior authorization support
Medication includedBilled separately
Home deliveryCostco pricing is pickup only
Specifications
| Service type | Telehealth weight-loss subscription |
|---|---|
| Care plan | $99/mo month-to-month, or $59/mo on an annual plan; Costco members 10% off |
| Plan includes | Video visits, labs, messaging, prescriptions and ongoing care |
| Medications | Wegovy (pill and injection), Ozempic, Zepbound and other weight-loss options |
| Compounded GLP-1 | Not offered |
| Costco pricing | Requires an active Costco membership; injections are picked up at Costco Pharmacy |
| Insurance | Prior authorization help |
| Data status | Prices from sesamecare.com and reviews checked September 2026 |
Full review
- Our score
- 7.1/10
- All-in from
- $248/mo
- Medication type
- FDA-approved brand-name
- Membership
- $99/mo ($59 annual)
Success by Sesame at a glance
Sesame is a U.S. telehealth marketplace, and Success by Sesame is its weight-loss subscription. Licensed providers prescribe FDA-approved GLP-1s, and through a partnership with Costco, Costco members can fill Wegovy or Ozempic at Costco Pharmacy for $349 a month. As of September 21, 2026, the care plan is $99 a month, or $59 on an annual plan.
What Sesame offers
Success by Sesame covers the Wegovy pill and injection, Ozempic, Zepbound and other weight-loss options. It does not offer compounded GLP-1s. Sesame also offers pay-per-visit care for erectile dysfunction, hair loss, dermatology and women’s health, including fertility, with visits from $37.
How Success by Sesame works
You book a video visit with a licensed provider of your choice, complete any labs, and get a prescription if it is appropriate. The care plan includes video visits, labs, messaging and ongoing care. For Costco pricing, the prescription goes to your local Costco Pharmacy for pickup.
What Success by Sesame costs
The care plan is $99 a month, or $59 a month on an annual plan, and Costco members get 10% off. Medication is separate: the Wegovy pill starts at $149 and reaches $299 at maintenance doses, Wegovy or Ozempic injections are $349 at Costco Pharmacy with $199 for new patients’ first two months, and Zepbound vials start at $299. An active Costco membership is required for Costco pricing.
Is Sesame legit?
Sesame works with licensed providers and prescribes only FDA-approved GLP-1s in its weight program. Its Costco partnership was announced in 2023. Costco pharmacy pricing is pickup only, which matters because Wegovy injections need refrigeration.
Who Success by Sesame is best for
It suits Costco members who want FDA-approved medication with a choice of provider and included labs. Look elsewhere if you don’t have a Costco membership, want home delivery of discounted injections, or want compounded medication.
Our verdict
Success by Sesame suits Costco members who want FDA-approved medication with a choice of provider and included labs. Without a Costco membership, or if you want home delivery, other programs are simpler. This review is based on research of Success by Sesame’s public pages and independent sources on September 21, 2026, not hands-on testing, and follows our methodology. TirzaSema has no affiliate relationship with Success by Sesame.
How it compares
Short answer: both mainly sell compounded GLP-1s, which are not FDA-approved. Mochi Health is cheaper at low doses, from $139 a month…
September 22, 2026
N
Short answer: Hims and Noom are different kinds of programs. Hims sells FDA-approved brand-name GLP-1s with a $149 membership, from $298 a…
September 22, 2026
Alternatives
Ro Body pairs FDA-approved brand-name GLP-1s at manufacturer-matched prices with a separate membership. All-in cost is $298 to $598 a month month-to-month, or from…
$298/mo
8.1/10
FDA-approved GLP-1s through Amazon Pharmacy: pills from $149/month cash ($25 with insurance), injections from $299. Visit fees extra. Checked Sept 21, 2026.
$149/mo
7.6/10
Mochi Health offers the lowest all-in GLP-1 prices we have checked ($139 to $278 a month) with board-certified providers and dietitians. The trade-off: its…
$139/mo
7.6/10
Frequently asked questions
About $248 a month at the Wegovy pill starting dose: the $99 care plan plus $149 medication. Wegovy injections at Costco bring it to about $448, as checked on September 21, 2026.
Yes, for Costco Pharmacy pricing. The Success by Sesame care plan itself is open to anyone.
Sesame providers help with prior authorization for GLP-1 coverage. The care plan is paid separately.
Sesame offers online visits for erectile dysfunction, hair loss, dermatology and women’s health, including fertility.
Sources
- Online weight loss program Sesame · checked September 21, 2026
- Costco Weight Loss Program Sesame · checked September 21, 2026
- Costco GLP-1 price 2026 GLP Chart · checked September 21, 2026
- Online doctor visits Sesame · checked September 21, 2026
- Sesame reviews Trustpilot · checked September 22, 2026
User reviews
No user reviews yet.
How we test
TirzaSema GLP-1 Provider Scoring Methodology
This methodology explains how TirzaSema scores GLP-1 telehealth providers and programs. Scores are a weighted average of five categories, and every review shows the full breakdown. Affiliate relationships and commission rates are not part of the methodology.
- Features · 25%
- Performance · 25%
- Ease of use · 15%
- Value for money · 20%
- Customer support · 15%
Prices are collected from each provider's public pricing pages and, where possible, confirmed during sign-up. Medication and membership costs are recorded separately, prices are shown by dose where published, introductory offers are labeled, and every price carries the date it was checked. When a review is based on hands-on testing we describe exactly what we did; when it is based on public information only, we say so.
FDA-approved medications themselves are not scored. They are listed as reference entries with their FDA-labeled uses and official manufacturer prices.
Some links on TirzaSema are affiliate links. Commissions never affect scores, rankings, pros and cons, or medical and regulatory information. See our Affiliate Disclosure.
Final verdict
Success by Sesame suits Costco members who want FDA-approved medication with a choice of provider and included labs. Without a Costco membership, or if you want home delivery, other programs are simpler.
S
Visit Sesame Success by Sesame (Costco)
$248/mo
T
Written by
TirzaSema Editorial Team
Research and editorial team
The TirzaSema Editorial Team researches U.S. GLP-1 prices and telehealth programs using official manufacturer, FDA and provider sources. Every review states whether it is based on hands-on testing or on research of public information,…
Related
Compounded GLP-1s with weekly check-ins: about $150/month all-in for semaglutide ($74.99 fee + $75 medication). Checked Sept 22, 2026.
$75/mo
6.5/10
Compounded GLP-1s from $99/month with insurance or $169/month cash on a 12-month plan, medication included. Checked Sept 22, 2026.
$99/mo
7.2/10
Compounded GLP-1s with a $135 membership: about $286/month all-in for semaglutide, or $297 on a bundle. Checked Sept 22, 2026.
$135/mo
6.1/10