Ozempic (semaglutide) injection

Once-weekly semaglutide injection from Novo Nordisk, FDA-approved for type 2 diabetes and related heart and kidney risk reduction. Not approved for weight management. Self-pay $349 to $499/month (checked Sept 20, 2026).

By Novo Nordisk Updated

At a glance

Self-pay from $349/mo standard price, before insurance
How it is taken Subcutaneous injection, once weekly
FDA status FDA-approved Not approved for weight management
Data last checked September 20, 2026 Verified

FDA-approved for

  • Blood sugar control in adults with type 2 diabetes
  • Reduction of major cardiovascular event risk in adults with type 2 diabetes and known heart disease
  • Reduction of kidney and cardiovascular risk in adults with type 2 diabetes and chronic kidney disease

Boxed warning: Risk of thyroid C-cell tumors (see Prescribing Information). Read the Prescribing Information. This page is not medical advice. Talk to a licensed clinician.

Self-pay price by dose

  • 0.25 mg, 0.5 mg or 1 mg$349/mo
    • 1 box of 1 pen (one month)
  • 2 mg$499/mo
    • 1 box of 1 pen (one month)

Verified on September 20, 2026. Source: NovoCare Pharmacy (novocare.com). Prices can change, so confirm the final price before you pay.

Other ways to pay

Introductory self-pay offer

$199/month for 0.25 mg and 0.5 mg, first 2 monthly fills, for new patients, through Dec 31, 2026 (checked Sept 20, 2026)

Commercial insurance savings

As little as $25/month for up to 3 months (maximum $100/month savings; government beneficiaries excluded)

Shipping

Free (NovoCare Pharmacy)

How the price compares

Wegovy$149Zepbound$299Wegovy$349
Ozempic (this page)$349

Lowest standard self-pay price per month from each manufacturer’s own pharmacy. Introductory offers and insurance prices are excluded. Medications, doses and approved uses differ, so this is a price reference, not a treatment comparison.

Key facts

Medication class
GLP-1 receptor agonist
Active ingredient
Semaglutide
Manufacturer
Novo Nordisk
Available strengths
0.25 mg (starting), 0.5 mg, 1 mg, 2 mg
Prescription required
Yes
Ozempic tablets
4 mg and 9 mg tablets are also sold; per-dose self-pay prices are not clearly published (Not publicly disclosed by dose)

About this medication

Ozempic injection is a once-weekly semaglutide medicine from Novo Nordisk. It is FDA-approved, along with diet and exercise, to improve blood sugar in adults with type 2 diabetes, to reduce the risk of major cardiovascular events in adults with type 2 diabetes and known heart disease, and to reduce the risk of kidney disease worsening, kidney failure and cardiovascular death in adults with type 2 diabetes and chronic kidney disease.

Ozempic is not FDA-approved for chronic weight management. Wegovy is the semaglutide product approved for that use. Self-pay prices below were checked on NovoCare Pharmacy on September 20, 2026.